ASI SponsorNucci, CarloCarloNucciGasperi, ValeriaValeriaGasperiTartaglione, RosannaRosannaTartaglione2020-09-172020-09-172007-07-01https://hdl.handle.net/20.500.13025/2168To evaluate whether high intraocular pressure (IOP)-induced ischemia is associated with modifications in the retinal endocannabinoid metabolism and to ascertain whether drugs that interfere with the endocannabinoid system may prevent retinal damage due to ischemic insult.AmidohydrolasesAmidohydrolases: antagonists & inhibitorsAmidohydrolases: metabolismAnimalsAntigensArachidonic AcidsArachidonic Acids: metabolismBenzamidesBenzamides: pharmacologyCB1CB1: antagonists & inhibitoCB1: metabolismCannabinoidCapsaicinCapsaicin: analogs & derivativesCapsaicin: pharmacologyCarbamatesCarbamates: pharmacologyCell CountChromatographyEndocannabinoidsEndocannabinoids: physiologyEnzyme InhibitorsEnzyme Inhibitors: pharmacologyEnzyme-Linked Immunosorbent AssayHigh Pressure LiquidHydrolysisIntraocular PressureMaleMessengerMessenger: metabolismOcular HypertensionOcular Hypertension: complicationsPiperidinesPiperidines: pharmacologyPolyunsaturated AlkamidesPolyunsaturated Alkamides: metabolismPyrazolesPyrazoles: pharmacologyRNARatsReceptorReperfusion InjuryReperfusion Injury: etiologyReperfusion Injury: metabolismReperfusion Injury: pathologyReperfusion Injury: prevention & controlRetinal DiseasesRetinal Diseases: etiologyRetinal Diseases: metabolismRetinal Diseases: pathologyRetinal Diseases: prevention & controlRetinal Ganglion CellsRetinal Ganglion Cells: pathologyRetinal VesselsRetinal Vessels: metabolismReverse Transcriptase Polymerase Chain ReactionSprague-DawleyTRPV Cation ChannelsTRPV Cation Channels: antagonists & inhibitorsTRPV Cation Channels: metabolismThy-1Thy-1: geneticsArticle Journalhttp://www.iovs.org/cgi/content/abstract/48/7/299754dcce098580fe1368eeb1fd