Thomas, M.O.M.O.ThomasShemmer, O.O.ShemmerBrandt, W.N.W.N.BrandtPaolillo, MaurizioMaurizioPaolilloKaspi, S.S.KaspiVignali, C.C.VignaliLira, P.P.LiraSchneider, D.P.D.P.Schneider2024-04-042024-04-042021-12-15https://hdl.handle.net/20.500.13025/6342We present three new Chandra X-ray epochs along with new ground-based optical-UV observations as the third installment in a time-series analysis of four high-redshift (z ≈ 4.1-4.4) radio-quiet quasars. In total, we present nine epochs for these sources with rest-frame temporal baselines of ∼1300-2000 days. We utilize the X-ray data to determine basic variability properties, as well as produce mean spectra and stacked images based on effective exposure times of ∼40-70 ks per source. We perform time-series analyses in the soft and hard bands, separately, and compare variability properties to those of sources at lower redshifts and luminosities. The magnitude of X-ray variability of our sources remains consistent with or lower than that of similar sources at lower redshifts, in agreement with the variability-luminosity anticorrelation. The mean power-law photon indices in the stacked Chandra spectra of our sources are consistent with the values measured from their archival XMM-Newton spectra separated by about 3 yr in the rest frame. Along with the X-ray observations, we provide near-simultaneous optical monitoring of the sources in the optical-UV regime. The overall variability in the optical-to-X-ray spectral slope is consistent with sources at lower redshifts, and the optical-UV observations display mild variability on monthly timescales. © 2021. The American Astronomical Society. All rights reserved..enjournal article10.3847/1538-4357/ac2e00https://iopscience.iop.org/article/10.3847/1538-4357/ac2e00